QCAPlus is a program for the quick, convenient and accurate quantitation of coronary artery lesion dimensions and stenosis from both DICOM CD and cine film.

QCAPlus Features:

1. QCAPlus automatically optimizes itself for computer display resolution settings.
2. Images of any resolution can be analyzed.

3. The following data can be automatically captured from the DICOM image data or can be specified by the operator at any time during the measurement process:
   1. Angiographic view.
   2. Anatomic location of the lesion.
   3. An operator supplied comment.
   4. Calibration catheter type and size.
4. Pushbutton controls are used to:
   1. Initiate manual editing of the automatically-detected walls, lesion ends and reference markers.
   2. Print a complete QCA report with the data and the image shown on the report screen, plus a full image frame showing the selected region of interest and Patient, Study, Series and Image information.
   3. Send a complete report by e-mail.
5. For each lesion, the following data are calculated:
   1. Minimum, maximum and mean diameter.
   2. Lesion length. The beginning and end of the lesion are determined automatically using statistical techniques.
   3. Stenosis reference ("normal") diameter. The reference diameter is determined automatically using statistical techniques.
   4. Percent stenosis.
6. A magnified view of the lesion and detected borders is displayed together with:
   1. The automatically-detected beginning and end of the lesion.
   2. The point of minimum luminal diameter (MLD) within the lesion.
   3. The automatically calculated reference diameter. Two reference diameters, distal and proximal to the lesion, are usually calculated and averaged. However, as in this case, if the lesion is distal to a major side branch, only a single distal reference diameter is calculated.

QCAPlus uses a state-of-the-art edge detection algorithm that is based on the least-cost minimization of the sum of the first and second derivatives of the vessel edge.

In cases of complex lesion morphology or anatomy, it is possible to supply the edge detector with the approximate location of both sides of the lesion instead of the centerline.

The accuracy of QCAPlus has been thoroughly validated at Stanford University and several other major medical research institutions. It has been used in numerous clinical trials.

QCAPlus can also be used to quantitate vascular angiography. Support is provided for calibration using vascular sizing catheters.

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Please contact Sanders Data Systems for more information.